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In silico approaches, including molecular docking and ADMET profiling, offer valuable insights into the bioavailability, blood brain barrier permeability, and binding affinity of polyphenols to pathological targets in AD
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Experiments addressing this question showed that also the IDO1 inhibitor BMT-297376 (a next-generation BMS-986205, see Fig
Yu P, et al
Giles F, Verstovsek S, Garcia-Manero G, Thomas D, Ravandi F, Wierda W, Ferrajoli A, Kornblau S, Jabbour E, Shan J, O'brien S, Albitar M, Kantarjian H
