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Ethical principles of the study complied with the European Directive 010/63/E, the Law on Amendments to the Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), the ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), Federation of European Laboratory Animal Science Associations (FELASA) recommendations, and the recommendations of the Ethics Committee of the School of Medicine, University of Zagreb

doi:10.1155/2016/7621942

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Intriguingly, MOTS-c behaves like an exercise mimetic in muscle: it is an exercise-induced peptide, meaning that during physical activity the levels of MOTS-c naturally rise
