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Its well-documented biological roles extend beyond the scalp to include anti-aging effects, oxidative stress reduction, and skin barrier repair (Pickart et al., 2015

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In this scenario, the failure to effectively clear damaged proteins and organelles leads to cellular dysfunction and eventual cell death (110)

Cellulite is the result of weakened skin fibers that are responsible for keeping the skin tight

To improve expression in insect cell culture, the native signal peptides were replaced by that of hemagglutinin (HA) in both the CTR and RAMPs constructs built in pFastBac vector