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Spectroscopic methods, including solution nuclear magnetic resonance (NMR) spectroscopy, have established GPCRs as highly plastic entities capable of sampling an equilibrium of conformations 9,10,11,12,13,14,15,16

GST-Pull Down Technology Introduction to protein interactions The functioning of biological systems is inextricably linked to protein-protein interactions, and important biological processes such as DNA synthesis, gene transcriptional activation, protein translation, modification and localization, and information transfer all involve the role of protein complexes