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Summary Keywords NAFLD, butyrate, obesity, gut microbiota, insulin resistance Citation Amiri P, Arefhosseini S, Bakhshimoghaddam F, Jamshidi Gurvan H and Hosseini SA (2022) Mechanistic insights into the pleiotropic effects of butyrate as a potential therapeutic agent on NAFLD management: A systematic review

Evaluation of Beneficial Metabolic Effects of Berries in High-Fat Fed Mice, J Nutrition and Metabolism (2014) ( Lingonberries halt effects of high-fat diet, News and Press Releases, Lund University (January 2014) ( Health Benefits of Lingonberries (Cowberries), ( cowberries-medicinal-juice.php)

All nutrients studied were classified by the USA Food and Drug Administration as Generally Recognized as Safe and sold over-the-counter without a prescription

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Access this chapter Similar content being viewed by others Abbreviations 4-HNE: 4-Hydroxynonenal 8-OH-dG: 8-hydroxy-20-deoxyguanosine AKR: Aldo-keto reductase ATF-2: Activating transcription factor ATM: Ataxia telangiectasia mutated CAT: Catalase CBR1: Carbonyl reductase 1 G6PD: Glucose-6-phosphate dehydrogenase GCL: Glutamate cysteine ligase GGT: Gamma-glutamyl transferase GPX: Glutathione peroxidase GS: Glutathione synthetase GSH and GSSG: Reduced and oxidized glutathione GSR: Glutathione reductase GST: Glutathione S-transferases HCC: Hepatocellular carcinoma HIF: Hypoxia-inducible factors HMOX: Heme oxygenase HNF4: Hepatocyte nuclear factor alpha MDA: Malondialdehyde MDR: Multidrug resistance protein MT: Metallothionein NADPH: Nicotinamide adenine dinucleotide phosphate NFE2L2: Nuclear factor (erythroid-derived 2)-like 2 NF-kB: Nuclear factor kB NQO1: NADPH quinone oxidoreductase 1 PI3K: Phosphoinositide 3 kinase PLC: Phospholipase C PPAR: Peroxisome proliferator-activated receptors PRX: Peroxiredoxin PTEN: Phosphatase and tensin homolog PTGR: Prostaglandin reductase RAR: Retinoic acid receptors RNS: Reactive nitrogen species ROS: Reactive oxygen species SOD: Superoxide dismutase TRX: Thioredoxin TXNR: Thioredoxin reductase References Albrethsen J, Miller LM, Novikoff PM, Angeletti RH