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Since diagnosis, the median (range) duration of the disease, motor fluctuations and dyskinesia was 7.9 years (3.712.2 years), 4.3 years (1.28.3 years) and 2.4 years (0.25.3 years), respectively, with very high dopa sensitivity (median: 78.9%

The tyloxapol model reproduces a pathophysiological state characterised by impaired lipid clearance due to LPL inhibition and consequent hepatic lipid overproduction (lipogenesis), a combination that underlies dyslipidaemia and non-alcoholic fatty liver disease (Reference Packard, Boren and Taskinen4Reference Tocto-Chaquila, Tarrillo-Peralta and Vega-Huamn7)

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doi: 10.1016/j.lfs.2019.117174