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Clinically, participants demonstrated a significant reduction in CARS scores (median decrease: 4.5 points

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For example, PGC-1, a master regulator of mitochondrial biogenesis, may play a critical role in skeletal muscle adaptation by promoting fiber-type switching from glycolytic to oxidative fibers [7]

La deplecin de GSH incrementa la toxicidad mediada por estrs oxidativo en estas enfermedades, ya que el tratamiento con N-acetilcistena, al restaurar los niveles de GSH, disminuye las alteraciones histolgicas e inhibe la muerte celular asociada a estas condiciones129,130