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Interestingly, rat pituitary adenoma GH3 cells lacking functional AIP, generated with CRISPR/Cas9 editing, showed a strong increase in GH mRNA levels and secretion, and a slight increase in cell proliferation compared to the parental GH3 cells (56)
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doi: 10.1155/2016/1575130 PMID: 27247935 Katzung BG (2024): Drugs used in heart failure (Chapter 13)
