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Under homeostatic conditions, 15-HpETE-PE is rapidly and specifically metabolized by the GSH-dependent GPX4 to the nonreactive hydroxy derivative 15-HETE-PE (6, 14)

Previous studies have shown that the ACSL enzyme family is essential for ferroptosis, highlighting that fatty acid activation to CoA ester is a key regulatory step in ferroptosis [25,26,27]

doi: 10.1104/pp.115.3.1277

First, vitamin C is not patentable
10.1002/art.20626 219 ParkJ.KwonO.AnH.-J.ParkK
