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Knocking down KRAS reduces the absorption of amino acids by colorectal cancer cells, while overexpression of mutated KRAS increases the expression levels of AATs [91]
PLoS One 8 , e55214 (2013)
Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells
Following single and repeat doses from 6 to 20 mcg/kg over 6 weeks, gross necropsy revealed no adverse organ changes
