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Description
Cytokines exert their effects by binding to specific receptors on the surface of target cells, triggering intracellular signaling pathways such as JAK-STAT, MAPK, and NF-B (Figure 2)
Similarly, ATM impacts cell death by regulating apoptosis, autophagy, and possibly necroptosis (Liang et al., 2013
doi: 10.1039/c9ra04248b 37 LiH.JiangF.WuP.WangK.CaoY
In comparison with asymptomatic volunteers, no association between Modic changes and trauma was found but rather with pre-existing disc degeneration
doi:10.1002/smll.201901507 32
