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Description
An ideal linker should remain stable in systemic circulation to ensure that ADCs maintain a stable connection between the antibody and payload during systemic circulation, thereby minimizing premature drug release and reducing off-target toxicity

10.1016/j.bbadis.2013.05.003 74

10.1074/jbc.R113.458810 23 GreenR

This dynamic interplay must be taken into consideration when targeting invasion in GBM

Headache is unusual
