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Description
The details of the multistep mechanism postulated for the reaction and the structural motifs of the several enzymes, which have been thoroughly investigated, cannot be described in detail
This is why the situation for patients still remains in a sorry state today
However, the moderate to severe forms have been associated with several comorbidities, such as psoriatic arthritis, Crohns disease, metabolic syndrome and cardiovascular disease
(273) ANSES
doi: 10.1016/j.cmet.2020.04.021
