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At pH 5.7, the histidine imidazole (pKa ~6.0) remains predominantly deprotonated and available for copper coordination

[DOI] [PubMed] [Google Scholar] 2.Hamed K, Alosaimi MN, Ali BA, Alghamdi A, Alkhashi T, Alkhaldi SS, et al

Preclinical models consistently show that combining serotonergic neuropeptides with SSRIs or MAOIs produces unpredictable neuromodulation that exceeds the therapeutic window of either agent alone

Obesity reviews 10: 4651 Kovalzon VM (1994)

The payment rate for 96360 is significantly lower than for 96413 because the drug does not require the same level of specialized handling and monitoring