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Compounds valuable for these efforts were analogues of glutamate that are conformationally constrained by the addition of substituents to the carbon backbone of glutamate or aspartate (b-hydroxyaspartate or methylglutamate derivatives), and the incorporation of ring systems (carboxycyclopropyl)glycines, aminocyclobutane dicarboxylates, or pyrrolidine dicarboxylates

Eligibility for prescription treatments is determined by a licensed clinician based on medical history, laboratory testing, and clinical judgment

Ideal for adults with BMI over 27 seeking sustainable weight management

The starting dose for severe deficiency is typically 1500mcg (the full dose of the 1ml vial) given daily or on alternate days for 1 to 2 weeks, or until haematological remission is achieved

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