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(1987) Mammalian tyrosinasethe critical regulatory control point in melanocyte pigmentation
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Mol Cell Biol 23(23):85768585

PEDF Pigmented Epithelium Derived Factor serpin serine protease inhibitor PEDF is a potent autocrine and paracrine hormone which blocks epithelial cell proliferation (including vascular epithelial cells, necessary for neovascularization), and promotes cellular differentiation, and is neurotrophic and neuroprotective

For this metric, we focus primarily on the spout of each bottle since this part of a bottle is usually the make-or-break factor in whether you'll enjoy drinking from a bottle or find it annoying
