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The replication and transcription of viral genomes are mediated by a polymerase complex consisting of two proteins: L and its cofactor VP35
However, while previous in vivo studies determined segmental range of motion decreases of about 1.0 to 1.3 per decade in flexion/extension 15,16 , the present study detected segmental range of motion decreases of 1.5 per decade in flexion/extension, suggesting higher effects of age on the passive flexibility of the cervical spine
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