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Set Realistic Expectations Be clear with your patients about what they can expect from each option

This means that while synthetic forms may provide the same essential vitamins, they are often isolated, whereas food-based vitamins are delivered alongside other essential nutrients in a more complex system

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Patients with existing medical conditions should consult a healthcare provider before considering use

It also aligns with epidemiological observations that folate supplementation around conception reduces neural tube defectsa clear demonstration of gene-nutrient interaction in neurodevelopmentand invites inquiry into whether similar principles apply to ASD (though the ASD relationship is undoubtedly more complex and multifactorial)