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Yes, glutathione is sensitive to heat and oxygen

The pivotal function of dehydroascorbate reductase in glutathione homeostasis in plants

Nat Chem Biol 7(8):504511 Droge W (2002) Free radicals in the physiological control of cell function

Cyanocobalamin is also contraindicated in patients with cobalt hypersensitivity because cyanocobalamin contains cobalt
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