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The correct mechanistic statement is subtler and less satisfying: the 3-AR is necessary for the chronic effect but is not the direct molecular target, and part of the acute effect is 3-independent through a route that has not been pinned down

When it is deficient, it can cause folic acid deficiency, which can lead to DNA synthesis obstacles and affect the development and maturation of red blood cells

Our electrophysiological results showed that tesofensine produced a stronger and larger modulation of LH ensemble activity in obese rats than in lean rats