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doi: 10.1016/j.diabres.2011.03.016

Senescent cells are permanently withdrawn from the cell cycle and generally develop a persistent pro-inflammatory phenotype, called the Senescence-Associated Secretory Phenotype or SASP(Coppe et al., 2008)

These changes dont have to be permanent

Cognitive changes may manifest as memory impairment, confusion, depression, or irritability

Astaxanthin prevents bone loss in osteoporotic rats with palmitic acid through suppressing oxidative stress