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Description
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Dysfunction of CI is a defining feature of circadian disruption and diet-induced obesity in adipose tissue, linking clock misalignment to visceral adipocyte hypertrophy, ectopic lipid deposition in liver and impaired glucose tolerance

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No published data tracks metabolic changes after discontinuation of 5-Amino-1MQ, but based on the mechanism, NNMT activity would return to baseline within days to weeks after stopping

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