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PMID: 4 CutlerDM

Dosage may be reduced to 0.5 mL weekly in patients experiencing gastrointestinal intolerance or increased to a maximum of 2 mL twice weekly for short-term metabolic intensification when supervised by a qualified clinician

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Until recently, it was not clear how mitochondrial dysfunction triggers the ISR

Herein, we demonstrate that single particle cryo-EM can be applied to a member of the pyridine nucleotide-disulfide oxidoreductase protein family, which includes crucial drug targets for several human diseases