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doi: 10.1016/s0021-9258(17)35292-4

Prevention requires identifying root causes and, where appropriate, using prokinetic agents, dietary strategies, and ongoing monitoring

THE TARGET CONCENTRATION APPROACH TO DESIGNING A RATIONAL DOSAGE REGIMEN A rational dosage regimen is based on the assumption that there is a target concentration that will produce the desired therapeutic effect

Although the brain makes up just 2% of body weight, it consumes 20% of the body's oxygen and energy supplies

Andersson L, Halenius A, Pulkkinen L, et al
