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Since vitamin B12 is primarily found in animal products, individuals following a plant-based diet may be at risk of deficiency

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Daily intraperitoneal administration for 11 days reduced body weight gain, decreased white adipose tissue mass by approximately 35%, and reduced adipocyte size, while food intake between treated and control groups did not differ significantly

Note that these two documented starting doses are worlds apart in size 150 mcg versus 2.5 mg is a roughly 17-fold difference