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Lifestyle factors such as poor diet, lack of exercise, and excessive alcohol consumption

S., Ramakrishnan R., Ferreira M., Dwyer T., and Jones G., Association Between Musculoskeletal Pain at Multiple Sites and Objectively Measured Physical Activity and Work Capacity: Results From UK Biobank Study, Journal of Science and Medicine in Sport 22, no

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Inhibition of GCL with buthionine sulfoximine (BSO) depleted glutathione rapidly, reflecting its short half-life (1-4 h) as a substrate of multiple enzymes (Fig