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lower thermal stability TT individuals exhibit: Lower plasma folate Elevated plasma 5,10-methylene-THF Mild hyperhomocysteinemia Reduced global DNA methylation

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doi: 10.1016/j.bbrc.2019.05.123 110 KanamoriYMurakamiMSugiyamaMHashimotoOMatsuiTFunabaM

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Conversely, FTO knockdown facilitates PTC progression
