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Cigarette smoking, which seems to contribute to the development and periodic flare-ups of Crohn disease, seems to decrease the risk of ulcerative colitis
Tirzepatide vs semaglutide 2.4 mg in non-diabetic obesity SURMOUNT-5 direct head-to-head, -20.2% vs -13.7% at 72 weeks: Aronne NEJM 2025

The medication is used for a wide range of indications

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The team also employed a more traditional fingerprint method the Tanimoto index that runs on a regular laptop
