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However, in a much larger randomized controlled trial of simvastatin and an antioxidant combination of 600 mg of all - rac --tocopherol (297 mg of RRR --tocopherol), 250 mg of vitamin C, and 20 mg of -carotene daily) in more than 20,000 men and women with CHD or diabetes mellitus, the antioxidant combination did not adversely affect the cardioprotective effects of simvastatin therapy over a five-year period (131)

Riboflavin (vitamin B2) and vitamin D are additional cofactors that may support glutathione recycling and endogenous antioxidant production

Antioxidant Support: Alpha Lipoic Acid and Vitamin C work together to neutralise free radicals, reducing oxidative stress and protecting cells from damage

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Its main functions are antioxidant, detoxification, and immune enhancement