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As an additional example to that of the trefoil peptides noted above, the peptide EGF (epidermal growth factor) is produced in human milk to promote growth of the gastrointestinal tract in newborn infants, but the same peptide aggressively stimulates the growth of breast cancer cells in adults

The implications of NNMT inhibition extend far beyond simple cofactor availability, influencing fundamental cellular processes including mitochondrial biogenesis, oxidative stress management, and epigenetic regulation

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