case report bpc-157 adverse effects Data: Promising, But Not Proven In Humans, Early animal studies suggest BPC-157 may reduce pain behaviors in inflammatory and non-inflammatory models, including reduced allodynia. But this The Hidden Risks of BPC‑157:
Description
More recent Phase 3 data from the REDEFINE 1 trial showed Cagrilintide monotherapy producing 11.8% weight loss over 68 weeks

Sikiric P., Hahm K.B., Blagaic A.B., et al

N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

And many of them, if not explicitly counseled otherwise, will do exactly that
Someone who wants to get back to running trails in Memorial Park has a different timeline and tolerance than someone who needs to be on their feet for work every day