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It is important to note that 23 of 38 trials in the meta-analysis did not include safety data, and many of the studies included had a small number of participants and did not use a rigorous methodology

220 Moreover, the prominent role of IDPs such as -synuclein, tau, and amyloid- in neurodegenerative diseases featuring protein aggregation, as well as other IDPs implicated in different diseases, may suggest their general clinical relevance 214 (see below in Section Causes and consequences of protein misfolding)

A continuacin, algunas recomendaciones basadas en evidencia cientfica y experiencia prctica: Antes del ejercicio Tomar L-carnitina entre 30 y 60 minutos antes de entrenar puede ayudar a optimizar la utilizacin de grasas como fuente de energa, mejorar el rendimiento y retrasar la aparicin de la fatiga

Acta Neurobiol Exp (Warsz) 81(3):286294

doi: 10.1152/physrev.00037.2003