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These evidence, while observed in cardiomyocytes and vascular smooth muscle cell metabolism, is also applicable to explain other important system functional imbalance in the lipotoxic state of high FFAs

[DOI] [PMC free article] [PubMed] [Google Scholar] Yang X, Sun X, Chen H, Xi G, Hou Y, Wu J, Liu D, Wang H, Hou Y, Yu J (2017) The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome

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[87] recently reported that renal dysfunction determined by estimation of GFR with the simplified MDRD equation, assessed at baseline (prior to trastuzumab therapy, after other chemotherapies) is associated with an increased risk of cardiovascular toxicity and complications following trastuzumab