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Further, DSePA, being a diselenide, can participate in the GPx cycle either by undergoing oxidation to seleninic acid by hydroperoxides (pathway I) or by undergoing reduction to selenol through thiols (Pathway II)

This could provide an explanation for the sizeable difference observed

Impact of probe compound in MRP2 vesicular transport assays

Metabolome analysis confirmed that sulfasalazine treatment decreased glutathione and cysteine-glycine levels in the kidney (Figure 4H)

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