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Heart failure or cardiomyopathy where central sleep apnea is common and often unrecognized

The ATM-Chk2-cell division cycle 25A (Cdc25A)-cyclin-dependent kinase 2 (Cdk2) pathway acts as a genomic integrity checkpoint and guards against radioresistant DNA synthesis ( Activating transcription factor 3 (ATF3) belongs to ATF/cAMP-responsive element-binding protein (CREB) family ( MDM2 is an E3 ubiquitin ligase that carries out the final step in the ubiquitination cascade, catalyzing transfer of ubiquitin from an E2 enzyme to form a covalent bond with a substrate lysine ( Pregnane X receptor (PXR, NR1I2, SXR) belongs to the nuclear receptor superfamily and is mainly expressed in normal liver, small intestine, colon, duodenum, and gall bladder tissues ( In this study, we investigated the role and the mechanism of PXR in the protection of liver and colon cancer cells from IR-induced DDR

doi: 10.18632/oncotarget.6203

In contrast to hemorrhagic strokes, ischemic strokes are currently more common, and their incidence is higher in older people

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