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C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

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10.1097/00000374-199803001-00013 PMID: 9622391 [DOI] [PubMed] [Google Scholar] [255].Clugston RD, Blaner WS

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While CKD is known to alter the gut microbiome, there is mounting evidence to suggest that TMAO is not only a biomarker for CKD, but also contributes to disease progression This points to diet, microbiome, hepatic TMA metabolism, and TMAO behavior as potential therapeutic targets