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This article might be especially effective because it's written by physicians for physicians, and carries the power of the Mayo brand, because it is published in the "Mayo Clinic Proceedings etc"

Headaches: Mild headaches are another possible side effect, which can often be mitigated by staying well-hydrated

But certain red flags make it especially important to get help from a clinician

Muscle Stem Cell Rescue: It has been shown to rejuvenate senescent muscle stem cells (muSCs), restoring the regenerative capacity of aged skeletal muscle and significantly increasing grip strength and torque in animal models

Avoid use if you have a severe nasal infection or blockage