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Analogous work was then carried out with unlabelled DCM in MOPS-buffered medium amended with 13 C-labelled bicarbonate, showing that DCMF incorporated carbon from CO 2 into the carboxyl group of acetate

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161 The noncanonical NLRP3 activation pathway is initiated by these caspases direct binding to intracellular LPS (iLPS) produced by Gram-negative bacteria, independent of TLR4, the conventional LPS receptor