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Horm Metab Res (2018) 50:5627

5.4 The stromal barrier: a multidimensional immune exclusion mechanism The PC TME comprises up to 90% non-neoplastic cells, with cancer-associated fibroblasts (CAFs) producing extensive extracellular matrix (ECM) rich in collagen, hyaluronic acid, and fibronectin

doi: 10.1111/jnc.14779 16 VisanjiNPBrooksPLHazratiL-NLangAE

These include: Vegetarians and Vegans : This is because the vitamin only occurs naturally in animal products

Cellular stress, inflammation, and metabolic dysregulation converge at this point
