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Description
The presence of high concentrations of tyrosine in the locus coeruleus and the substantia nigra leads to increased melanin synthesis which confers on these brain regions a dark bluish coloration observable in brain sections

There was no significant difference in EFS and OS between the randomized arms

5f), that could block the opening of this GSH gate
Reduced glutathione (GSH) is a potent antioxidant and protects cells from Reactive Oxygen Species (ROS)

Acknowledgments The authors gratefully acknowledge the support of Sidra Medicine, Qatar, for providing institutional resources that facilitated this review
