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Nonetheless, in organotypic hippocampal cultures with preserved neuronal-glial interactions roxadustat decreased the neuronal susceptibility to ischemic stress, which was largely prevented by restricting glycolytic energy production through lactate transport blockade
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Clinical Perinatology
Zimmer et al., 2000) and acts as a metabolizing enzyme by increasing the uptake and absorption of vitamin E and hence facilitates an anti-proliferative effect most notably in prostate cancer and as a tumor suppressor in cancer through a non-vitamin E mechanism
Schrder, Scott R
