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The SARM1 axon degeneration pathway: Control of the NAD(+) metabolome regulates axon survival in health and disease
doi: 10.1016/j.foodres.2025.117923 83 YuY

This heterologous enzyme comprises the ChlI (40 kDa), Chld (70 kDa), and ChlH (110 kDa) subunits ( Chelation of Mg to the porphyrin ring occurs in two stages ( 2+ , while subunit H binds to protoporphyrin IX and Mg 2+

Nonetheless, these results highlight a key role of mitochondrial iron in mediating ferroptosis, suggesting that targeting mitochondrial iron overload may represent a new strategy for preventing ferroptosis
