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Given that these inhibitory effects have been demonstrated in cultured GH-producing cells, they appear to be paracrine and independent of any action on hypothalamic somatostatin release, although it would be interesting to analyze whether nesfatins play a role in hypothalamic control of the synthesis and secretion of pituitary GH exerted by SS-GHRH, or on the neurotransmitters involved in this hypothalamic regulation of GH

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Active RhoA detection The detection of GTP-RhoA level is based on the specific binding of the Rho-binding domain (RBD) of Rhotekin to GTP-RhoA with the commercial active Rho detection Kit (#8820, CST)

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Wang L., Wang H., Song D., Xu M., Liebmen M

J Immunother Cancer (2023) 11(8)