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Of ROS species involved in LPO, hydroxyl and hydroperoxyl radicals are primary contributors
The nuclear transcription factor NEF2 serves as an inducer of SLC7A11 expression, while tumor suppressor genes TP53, BAP1, and BECN1 downregulate SLC7A11 expression [40,41,42]

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Br J Pharmacol 174, 13251348.CrossRefGoogle ScholarPubMed Hansen, M, Rubinsztein, DC & Walker, DW (2018) Autophagy as a promoter of longevity: insights from model organisms
