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Description
Firstly, a probe (containing specified alkyne and an IAM group) will react with the thiol group in a protein ( via IAM group) to form the probe-protein intermediate

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doi: 10.1016/j.phrs.2021.105432

PGC-1, as a key regulator of mitochondrial biogenesis and transcriptional regulator, is involved in the regulation of BACE1 transcription
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