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Nonetheless, the clinical potential of microbiome modulation, whether through diet, prebiotics, probiotics, live biotherapeutics, or microbiota-derived compounds, is becoming increasingly tangible (Ben-Yacov et al., 2023

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However, further mechanistic studies are needed to determine the direct effects of choline availability on eosinophil activation and function and to assess the therapeutic potential of dietary choline supplements (95) in managing hyperreactive eosinophilic conditions, such as eosinophilic myositis or gastrointestinal disorders