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In this review, we summarise the complex metabolic pathway of Vitamin B12, the inherited and acquired causes of Vitamin B12 deficiency and subsequently highlight the disparate international practice of prescribing Vitamin B12 replacement therapy

J Food Biochem

For more details on the correct use of these differing dietary B12 recommendations, see Chapter 8b: Evaluation of nutrient intakes and diets

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During therapy, B12 levels may rebound quickly after injections, but functional markers like MMA and homocysteine can reveal whether tissue-level B12 status is truly improving