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Description
These hormones regulate melanogenesis not only through genomic and non-genomic signaling pathways that directly modulate melanogenic enzymes (e.g., TYR, TRP-1, TRP-2) and transcription factors (e.g., MITF) but also by interacting with oxidative stress, inflammatory responses, and vascular remodeling, thereby establishing a complex molecular network that exacerbates hyperpigmentation

It protects the delicate mitochondrial membranes from the oxidative damage caused by the reactive oxygen species (ROS) generated during viral infections

Selenium contributes to the maintenance of hair and nails under normal conditions

doi: 10.1038/nature06639

Muhammad W
