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Boxes represent the 25th, 50th, and 75th percentiles, and whiskers represent the 10th and 90th percentiles

TR nuclear hormone crosstalk with other metabolic pathways, especially the nuclear receptors PPAR, LXR, and PGC-1, is essential for the T 3 regulation of cholesterol metabolism and transcription of lipogenic and lipolytic genes

Skin and coat appearance are also shaped by broader nutrition and barrier support, not single ingredients (HAE, 2024)

10.4049/jimmunol.164.1.488 28

Based on preclinical studies, it has been suggested that L-carnitine supplementation could limit the imbalance between protein anabolism (synthesis) and catabolism (degradation) that leads to skeletal muscle wasting (42)
