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A 2008 study by Parihar, Kunz, and Brewer, published in the Journal of Neuroscience Research , found that aging neurons have measurably lower resting NAD(P)H and lower glutathione content compared to younger cells

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In the same study, both top and bottom quintiles of plasma betaine concentrations were associated with an increased risk of secondary acute myocardial infarction

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[137] While it's possible that intravenous vitamin C might not be effective after ischemic stroke when oxidative damage has already occurred, another possible explanation for the lack of efficacy observed in this study was the low dose used, since intravenous vitamin C doses are typically administered in gram quantities

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